Archive for the 'biotech' category

A day in the life of a Mother-of-a-5-month-old/Scientist in biotech

Oh my goodness it’s so hard to be a working mom!  I always respected working moms but it is so much harder than everyone else makes it look!  First off, leaving my little man at daycare was really hard at first… and then it got hard again when we all got sick… and just today I got scared again because another mom in my son’s class told me that they wrap the babies in muslin and put them on their stomachs for naps-that’s not normal right???!!! Secondly, because of where we work and where the daycare is, I get to/have to do both drop off and pick up for our little guy. It really makes me evaluate how I use my time at work because I don’t want him to stay at daycare for too long (and we have a 10hour max each day). Lastly… pumping… oh man, trying to make time to pump even twice a day (30mins with set up and clean up each time) is really hard. Don’t get me wrong, I LOVE being a mom and I still get so much satisfaction from work. It is all worth it and I’m figuring out how to juggle everything, but it is hard. So here’s a look at a day in my life.
12am-6am wake up a million times to flip the baby back over (he can roll onto his belly but it freaks him out and he wakes up crying), or put his pacifier back in, or feed him.
6:15 wake up and give the baby his reflux medicine. Then get up and get ready for the day.
6:45 get the baby ready and feed him again.
7:15 kiss my husband goodbye and wave to the puppies (he takes care of them in the mornings) and get going
7:45 drop the baby off at daycare
8:00 get to work and get some breakfast, check and respond to emails
8:15 prep solutions etc for my experiment for the day (I’m setting up a new assay so I’m excited to get going)
9:30 stop everything to head down to the “mother’s room” to pump/read papers/email/zone out. When I first got back to work I was able to pump enough for my little guy easily in 2x/15min sessions each day. Then I got sick and my supply tanked. I was pumping 25mins 2x/day and getting only half of what he needed. Luckily I had a good sized freezer stash to hold us over (we tried to get him to take formula but wasn’t having it). I realized last week that I had also stopped eating enough for two so I’ve upped my caloric intake and voila! My supply is back, fingers crossed I can keep it up. Ps a pumping bra is essential!
10:00 head back to the lab and start my assay
12:30 finish up and head down to lunch and relax with friends
1:00 pump again.
1:30 sort through and analyze my images from the histology core
3:30 meet with a new mentor in another department – I can’t wait to tell you guys more about it in my next post!
4:15 grab my pumped milk and head out
4:30 pick up my little one
5:00 get home, give the baby meds, feed dogs, start dinner and to get some errands done while baby plays
5:15 hubby gets home and we tag team – playing with baby/dogs and getting dinner ready
5:30 eat dinner
6:00 the whole family walks the dogs up to the park and watch the sunset. 6:45 get home, get little one in the bath
7:15 all snuggle in the baby’s room, feed him while hubby reads him to sleep
7:45 pump and watch tv
8:15 prep for tomorrow. I’ve started showering at night, pulling my clothes for the next day, preping lunch and getting everything I can put by the front door, this seems to help everything go smoothly in the mornings. Get ready for bed
9:00 get into bed and unwind. Try to get some sleep before the little one wakes up, usually around 1am.


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When Your Pregnancy is a Job Hunt, or The Amazing Community of Women in Science Part II

Several months ago, I wrote about the experience of being 5 months pregnant and told that my postdoctoral mentor was leaving our institution.

This was my chance to leave my oppressive pit of a working environment without burning any bridges. This meant trying to find a new position before giving birth so that I might avoid unemployment. This was exciting. This was terrifying.

Four months later, I have a fellowship and a job lined up for after my “maternity leave” [read: unemployment]. I gave seminars and had interviews at 7 months, 8 months and 9.5 million months pregnant and each time have been pleasantly surprised that I portrayed myself first as a capable scientist and then as a pregnant woman (inevitable shortness of breath notwithstanding…). This experience has shown me what women are capable of, and given me a newfound respect for myself.

The Process:

Despite now feeling that this journey has ultimately been a success, I have never had a more confused, frustrated or nihilistic perception of my career and future. It was at once a frantic crisis and insignificant. During this experience, I not only interviewed for academic postdocs within my current institution and at nearby institutes, I applied for industry scientist positions – something I thought I would not do for several years to come, if at all (and thanks to very active support and a recommendation from our very own Curiouser&Curiouser, I was even invited to give a job talk!).

But all of these interviews were hard. Because throughout the whole process, I was so disenchanted with my previous aspirations, and overwhelmed with the possibility of entirely changing my career track when all the while all I actually cared about was keeping my little imminent offspring healthy and becoming a new parent. How could I possibly communicate my interests and goals in an honest way when my thoughts were in such an unmotivated place? Somehow, I channeled Ragamuffin circa 2016 for every interview and she did me a great service by masking my current intellectual turmoil.

I narrowed my opportunities down to two academic labs and an industry position (I had way more options with diverse potential than I expected, which made the whole process even more confusing). The industry opportunity continues to play out, but I expect this was more a chance for me to introduce myself and be remembered favorably when I apply for a more fitting position in the future. Of the academic labs, one lab was small and very low-key and would probably have prepared me well for a future industry position. The other lab was mid-sized with high expectations and would probably prepare me equally well for either a career in industry or academia. The small lab required finding my own funding, and only when I had secured that was I able to really consider which lab I preferred. It took me a month to decide.

What if I make the wrong choice because of pregnancy brain and end up hating my next position?

What if I misinterpret what lies ahead like I did with my current postdoc lab and wind up losing another year of productivity?

What if it turns out that my career goals change drastically after I become a parent and I chose the wrong work environment to accommodate whatever those are?

I calmed down a bit when my self-employed husband’s income (which crashed the day my PI announced his departure) started to recover, and I felt less guilty about the fiscal implications of staying in academia.

And after several communications with each of the PI’s (both women), I chose the mid-sized lab with high expectations because I felt a strong connection with the PI that made me believe I wanted to and could continue (for now) down the path I would have chosen a year ago. Because there were no wrong choices, only the next chapter of life.

Closing Up Shop:

I left my current lab last week to begin maternity leave. I put all the materials I’ve developed over the last year in cryostasis and labeled them to be shipped to my adjunct faculty oppressor so that he can continue my work (ostensibly) and take credit for my contributions (inevitably). I photocopied my lab notebook, backed up all my meticulous protocols, and archived my server emails so as to have a record of my contributions if I need to defend my right to authorship in 5 years (undoubtedly). I said heavy goodbyes to the colleagues who have been such wonderful influences over the last year, and begrudgingly said an adulatory and pleasant farewell to my PI. And left behind a year of professional struggle and wasted scientific effort.

 

And now, I am ecstatic to spend the remaining two weeks of my pregnancy job hunt-free. Bring it on.


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Job Interview Questions

When I was first interviewing for jobs I got the question “what are your career goals?”  The question was something I had given a lot of thought to but I’d never actually transferred these ideas into an interview appropriate answer before.  I muddled through that interview, but I realized I could do much better if I forced myself to put my thoughts into actual words, so I started preparing for interviews by writing down potential interview questions and answers.  I think this has helped to make me more clear and succinct (when I’m nervous I tend to ramble) and I like that I get the chance to review what I said for previous interviews.

Recently, a lot of my friends and family have been applying to new jobs/promotions and I’ve been running practice interviews with them.  It feels good to have another use for all the research I put into finding/coming up with/remembering potential interview questions, so I’ve decided to also compile them here for our readers.  Please feel free to comment with any other questions you’ve come across.

Two general thoughts on interviewing…

  • Make your answers short and specific.
  • Keep things positive, if you want to highlight aspects that you didn’t like, try to put a positive spin on things, eg show how would improve things.

Best of luck to all the job applicants out there, I hope this helps!

Questions

– Tell me about yourself/how would you describe yourself?  This should be geared toward the job you are applying for not a general introduction.

– Tell me about your experience at ____ prior company/lab___.

– What did you like about ______ prior company/lab___?

– What do you wish was different about ___ prior company/lab___?

– Why do you want to leave your current position?

– What do you know about this position/company?

– What techniques/methods are you accustomed to using?

– What is your work style/how do you like to approach your work?

– What are your top 3 strengths/weaknesses?  Make sure to tailor this to the position.  If it was a R&D job I might feel ok mentioning that I get nervous talking in front of crowds (true) but if I was going for a science liaison position I would probably choose something else.

– Why are you interested in this job/company/institution?

– What are your expectations for this job/company?

– What is your management style/how do you like to be managed?

– Tell me about how you like to interact with your lab mates.

– How do you deal with conflict?

– What do you bring to this job/company?  This is an awesome opportunity to brag and really highlight why you should get the job

– Describe a setback and how you overcame it.

– Describe a conflict and how you overcame it.

– Describe a time you were working under pressure to get a project completed.

– Describe a mistake and what you did to correct it.

– Give an example of when you used scientific problem solving/a creative scientific approach to solve a problem.

– What motivates you scientifically?

– What are your career goals?

– Why are you leaving academia?

– What are your hobbies?

– Do you have any questions for me/us? You will probably use some up during the course of the conversation, so have a bunch.

– Do you have any concerns for us?

– How much do you want to make? I hate this one… I always try to say something like; I’m excited about this position and I would just like to be appropriately compensated. Ugh.

 

 

 


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When Your Postdoc Mentor Switches Institutions, or The Amazing Community of Women in Science

I am 9 months into my first postdoc. I am 6 months pregnant. I will be unemployed two days after my son is due to be born.

One month ago, my postdoc mentor announced that he has accepted an incredible promotion at a university on the other side of the United States. For several reasons — including having just relocated my family, the strain on my husband’s career and the expectation of a neonate at the time of the Great Move – I will not be translocating with the lab.

My “mentor” made clear to me last week that he will not be renewing my contract two days after I give birth even though he will remain at my institution for another 1-3 months. Even though he will renew current university contracts with at least one other postdoc for several months and lied to my face about doing so. My Postdoctoral Union, the Academic Resource Center and the university Business Office have nothing to say about this. I have no protections in this situation; it is my “mentor’s” choice.

I have spent three quarters of the last month in debilitating pain because my dentist managed to kill a perfectly healthy tooth and pregnancy hormones exacerbated the effects of necrosis, inflammation and infection (lack of effective painkillers did not help either). The other quarter of the month I spent frantically scouring my current institution for potential academic postdoc opportunities in a sea of unknown or inadvisable labs. Labs that are very unlikely to be willing to contract a woman who would just entered maternity leave at the time of ideal onboarding. By this time, I may or may not have transferable salary from any of the three fellowships I’ve just finished applying for. Likely the latter, which prevents me from sweetening the deal.

‘Just find a new postdoc position by next month,’ my “mentor” advises. ‘That way you can spend a month or two in the new lab before going on maternity leave. No one would refuse you a position because of the pregnancy, that would be outrageous.’ He proceeded at my overly laudatory request to recommend potential employers who were strikingly ill-suited to my career goals or experience.

“Mentorship”.

Given the timing of my imminent unemployment and my need for not only neonatal care but regular treatments for my autoimmune disorder, avoiding a lapse in health coverage is – for the first time in my life – a priority over my career aspirations. In a time when COBRA and biologic therapy are unaffordable, my husband and I must re-budget dramatically to pay our mortgage and loans and keep our neonate (and ideally, myself) alive. I have therefore stretched my feelers into a world I was not prepared to join for several years if (and only if) I could tell with more certainty that professorship was not in the cards: non-academic science.

Mid-pregnancy does not feel like the right time to be making a career-altering decision that could mean closing the door to academia for good. Then again, if my choice is between sacrificing my family’s well-being for a sliver of a chance at a reasonable academic postdoc or sacrificing my pipe dream for a potentially happier and more rewarding life, the latter is my clear choice. This is not what everyone should or would choose in these circumstances. This is likely not what I would have chosen 5 years ago. But I love what my life is becoming and am prepared to shift gears if it means being able to do rigorous, ethical and productive science in a healthy way.

Despite the extraordinarily strenuous timing, this transition is somewhat of a blessing as I have had a miserable 9 months with my current absence of any form of mentorship, the embarrassing dysfunction of this world-renowned lab and the excruciating oppression of both my “mentor” and a male adjunct faculty. This is my way out without being the one to set fire to any bridges.

While most days I feel lost and hopeless, I am grateful to no longer be in debilitating pain and I strive to protect my active little belly parasite from my own distress. I am fueled now more by adrenaline and awe of the circumstances than by fear and depression. And I have benefited from some wonderful advice.

You know who has advised me? Not my male “mentor” who has all but thrown me into the gutter. Women. Women who are senior post docs in my lab. Women who write for this blog. Women who have agreed to interview me for positions in their labs at my current institution. Women who have talked through the circumstances of my potential unemployment and financial crisis with me. Women who have helped me identify solutions. The woman who I interviewed with today.

The ball is rolling in a sluggish but mostly forward direction. Today I have hope because of the women I have met in science.


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Mission Statement

There is so much that I love about my career as a Research Scientist in BioTech. I love the creativity and intellectual stimulation, the teamwork and independence, the opportunity to apply expertise but always keep improving and learning, and I love the puzzle of it all. But sometimes I feel drained, and recently I’ve been in a bit of a funk. I think part of it is from our continued fertility struggles; but I start thinking that maybe I’m not in the right job or even the right line of work…. Maybe I want to run away and be an illustrator or a farmer. I should go live on a commune and teach kindergarten in a tree house. But when I really sit down and outline what I want out of a career/my life I realize (again) that I’m doing it, I have my perfect job. So why do I feel so blah?

? I recently came across a blog post entitled “why a personal mission statement is key to career bliss.”  Based on this maybe the question I need to be asking myself isn’t what I want to be, but rather who do I want to be. I like this idea! I don’t need go external and look for a new passion project or do anything drastic to find my happy place, I just need to be more mindful of my “core motivators” and make sure that I honor that thought in my daily life. Here is my first attempt at a personal mission statement, it’s pretty broad, but I like that it applies to my work-life and my life-life.….

To be a compassionate and creative person who contributes to, and supports teams trying to make the world a better place.

I would love to hear from you, do you have a mission statement?  Has it helped you?


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Why I stopped faking it

When I was in grad school I felt like I wasn’t good enough and at the same time that I deserved to have it all – perfect grades, grants, awards, fantastic publications, a great social life and a happy family. My way of trying to achieve this was by acting tough, and it actually kind of worked.

Early on my PI told me that if I needed something from him I should keep “nagging” him (his words) if I wanted it done. He was right, he was a very busy man and I learned to do what I needed to do to get things done and I had a successful and happy grad career. At the intro to my defense he proudly told a story about the lengths to which I went to make sure that he signed paperwork in time for submission (I followed him to the restroom and waited outside until he came out). But acting all the time took its toll. By the time I was looking for a postdoc position I was burnt out (I know, almost everyone is burnt out by the time they defend), and I was so tried of trying to “fake it ’til I make it.”

The way this feeling manifested for me was in my choice not to pursue invitations to interview at top tier labs, and instead to join a good, but not a stretch, lab at a good, but comfortable University. I just wanted to go somewhere where I could do good work, be a good lab-mate and collaborator and be supported in turn, and I thought I had found just the place. It nearly broke my heart when I learned that my new PI had hired another postdoc at the same time as me and had given her the same project as me. I still don’t know if this was the result of a brain fart or if it was a may-the-best-researcher-win type thing, but it sucked! She was a very nice person and once we realized what was going on we were totally open with each other about what we wanted to do with the funding and the project and we made the best of the situation… but it broke me down. I stopped pretending I was strong and acting tough. I let the fact that I was sad about the situation show and completely shifted my research topic (for multiple reasons) – we were already competing with the rest of the research community, I didn’t want to have to compete with my lab-mates.

When my husband and I got the opportunities to move to California I was thrilled. It was a chance to move on! I’d decided that I wanted to leave academia and see if biotech was a better fit, but I’ve still not put back on that mantel of toughness. I’m a lot truer to myself and my feelings now, I’m not sure if that is a good thing or not. It means that my insecurities are more pronounced; I’m suddenly a lot more visibly nervous giving talks. I also push myself less, I’m less focused and for better or worse I’m not trying as hard to have everything right now. I feel like I lost my edge when I gave up pretending that I was perfect and stopped grabbing for “all the things.” On the other hand I’m happier and less tired all the time. I get to prioritize my personal life along with my career. And now that I’m less concerned about credit and what I deserve, I think I’m a better collaborator and team-mate. Things that used to drive me crazy, like when people would co-opt my ideas without credit, don’t affect me the same way. When I realized this change I initially felt terrible, giving up my (righteous?) entitlement seemed so sad, but most of the time now, I don’t see it that way. I think there is a healthy line that I’m still learning to walk between wanting everything and accepting anything. I hope as I become more honestly confident that I’ll find my middle ground.


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Working Through: Fertility issues in the workplace

My husband and I stopped trying not to get pregnant 6 years ago. About 3 years ago we started trying to get pregnant and just over a year and a half ago I had my first miscarriage. We found out that there was no heart beat at 9weeks, confirmed it at 10weeks and had a D&C at 11weeks. One of the reasons why it took us so long to actively try to conceive was my fear of losing the pregnancy. I remember thinking that it would be an unsurvivable experience for me. Now I’m at a point where I can say that I appreciate the extra time before starting my family and the strength I found in myself and my relationship with my husband. That being said, miscarrying is horrible. Each time I lost a pregnancy I obsessed about all of the things I might have done wrong to cause the loss. Was I too stressed out, did I eat the wrong thing, was my shampoo poisoning the baby, did I touch the wrong thing at work?

A number of my closest friends and my sister were pregnant right around the time of my first pregnancy and it felt like my miscarriages made things awkward for us. They were worried that talking about their pregnancies/babies would hurt me, (and maybe they were a little right, I swore off of facebook for a while because it seemed like everyone was pregnant except me) but when they stopped complaining to me about swollen feet and colicky babies or telling me about the little joys like feeling the fist kicks and seeing first steps I felt even more isolated. I worried about talking to them too much about my miscarriages, I didn’t want to worry them about the viability of their own pregnancies. I knew it was irrational, but I felt that by talking with them about what happened my dark cloud would contaminate their happiness, which was the last thing I wanted. Friends asked me if I was seeing a fertility specialist (I’ve learned I shouldn’t call them infertility specialists because that sounds negative) which is a totally reasonable suggestion, but one that I was reluctant to follow up on for a long time. For me, this whole process has been confusing. On one hand, I want to be a strong feminist and be outspoken about the fact that I have had miscarriages to help other women feel less alone. On the other hand, I want to curl up in a ball and cry while telling myself/everyone that everything is fine and the next time will work out.

It has been almost a year since my last pregnancy. 4 months ago we finally started seeing a specialist. We did all the tests our Dr. recommended and everything is normal. There are little things that the Dr. points to and says this or that maybe on the low or high end of normal, but nothing that we can point to and say, yup that’s why it’s been so long or that’s why I’ve lost all of our prior pregnancies. The one good thing about all of this waiting, is somehow in the last few months I feel like I’ve come closer to a kind of acceptance in regards to this process. I am cautiously optimistic each month and each month I am disappointed, but it doesn’t devastate me each time.

All the while I have been struggling with these miscarriages and fertility issues I’ve been working, and it has not always been easy. At my last job I told my boss that I had miscarried and that I would need a D&C because I needed to take the following day off. She is a great boss and mentor and was as supportive as I could possibly have hoped for. About a year ago I changed jobs, and while I like my bosses, I chose to try to be more professional and less open about my struggle. It might be misplaced, but I worry that they will be mad/frustrated/disappointed/concerned-about-how-the-work-will-get-done if they find out that I am pregnant, and since I have had so many false starts I don’t want to have that negative interaction before I have to. Industry jobs are very volatile and I always want to put my best foot forward. Reasonable or not, I worry that people would consider (consciously or not) my future maternity leave against me if there was a restructuring of my department. While I stand by my decision to maintain my privacy in my professional life, it does pose some problems. Infertility testing and treatments are time consuming. There are a lot of timed tests that I/we have to go into the lab or clinic for. At first I would let people know that I had a doctors appointment, but then my boss started asking if I was ok and I got paranoid that he either thought I was really sick or he would assume that I was already pregnant or he would think I was interviewing for other jobs. So I now I’m trying to be more vague or slip out without saying anything, but that also feels very obvious and slightly disrespectful especially when I am missing meetings.   I worry that people will think that I am just shirking my work. I don’t know what the right thing to do is. It would be great if more of the appointments could happen before/after work hours or of the weekends… but that’s just wishful thinking as far as I can tell.

I’m writing this post on the eve of my first IUI (intrauterine insemination… basically they collect the sperm spin it down and stick it into my uterus through a catheter, woo hoo!). This morning we went for the ultrasound and unfortunately my follicles were a little more ready than we expected… so I had to run out to the pharmacy and take my (injectable) ovulation stimulating medicine immediately. I had a meeting at 9:30am so I got the drug and injected myself in my car in the parking lot (there are no sharps containers in my work bathrooms, I didn’t feel right injecting myself in the lab where there are tons of sharps containers, and I didn’t want to wander around work with my needle and medicine so I decided my car was my best option). I know to people who have to give themselves injections all the time it probably doesn’t sound like a big deal but it was my first time injecting myself ever and it took a little bit to convince myself to stick the needle in, maybe it was a good thing I was running late for my meeting. It makes me wonder what things other than having a pumping room would make fertility struggles, pregnancy and having kids easier to balance with work? Does how hard it can be to get pregnant (especially for those of us no longer in our 20’s) have anything to do with the high attrition rate of women in science? I know it has impacted how much of a go-getter I am at work and how much I “lean in” since I don’t want to have to back out if I have an appointment/have a crappy pregnancy/go on maternity leave (and yes, I know this is exactly what Sandberg says not to do).

Overall, I’m excited and a little nervous about the IUI but I also appreciate that for the moment my life is beautiful as it is. My partnership with my husband is stronger now than ever and I have hope that our family will grow one way or another. In the mean time I’m trying to learn to be more chill/sneaky? about this personal process at work and I’m having an amazing time being an aunty to my niece and all my friends’ adorable babies.

One last thought for the moment. I really appreciated what Mark Zuckerberg did by posting his fertility struggles along with his pregnancy announcement. One thing that makes me extra thankful for the opportunity to share my experience anonymously is the ability to talk about the process before we have the safety of having a successful pregnancy. Thanks!


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Ideas (About Science Careers) That Should be Retired

I love podcasts! The other day I was listening to Freakonomics, one of my go-to podcasts, and they started talking about “ideas that must die.” The hosts ask scientists what popular scientific ideas should be gotten rid of because they are impeding progress. The first example is from Sarah-Jayne Blakemore, a professor of cognitive science at University College London who wanted to debunk the idea of people being either left or right brained. Other ideas offered up to the chopping block included the power of statistics, the relevance of mouse models and that life is sacred. While I didn’t agree with all – actually most – of the suggestions it seemed like an interesting topic to explore for the blog. So I’ve come up with a list of misconceptions about careers in biology that I think should be retired.

  1. Research Professors have better/more flexible schedules than other career options. This is crap. All of the tenured and tenure-track faculty I know work their butts off non-stop and many non-academic jobs allow you to work around scheduling conflicts… it’s all about getting work done.
  1. Leaving academia is shameful and people who leave are not as smart/motivated/are only interested in the money (I’m still working on this feeling for myself but I love what Perima, StrongerThanFiction and Torschlusspanik have to say about careers outside of academia)
  1. PhD’s always make more money than researchers who have bachelors or masters degrees. There are a ton of online debates about whether PhD’s earn more than researchers with bachelors or masters. The bottom line is, it’s not clear – so don’t go to gradschool for the money!
  1. Grad school is super hard and a terrible, horrible, torture fest. Yes, I had crappy days and at times it was hard to juggle everything, but it was a fantastic experience. I have way more good memories about my time in grad school than bad ones.
  1. Academia produces the highest quality work. I was surprised when I got to industry and found out how often we try and fail to replicate published results, even when consulting with the original authors. I heard a lot of talk about how the pressure in academia to publish diminishes the quality of papers. On the other hand, scientists in Biotech have their own pressures that can also be reflected in publications.
  1. Researchers in Biotech have no scientific independence. It is true that you are usually hired to work on specific research topics. But I have found that I am able/encouraged to bring up new ideas and follow up on diverse research questions. I don’t know if this is the norm, but I have been very pleasantly surprised at how much interesting research I get to do.

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